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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK2
All Species:
22.73
Human Site:
S616
Identified Species:
62.5
UniProt:
P78362
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78362
NP_872633.1
688
77543
S616
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Chimpanzee
Pan troglodytes
XP_001160812
687
77411
S615
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Rhesus Macaque
Macaca mulatta
XP_001088614
687
77455
S615
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Dog
Lupus familis
XP_849273
686
77402
S614
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Cat
Felis silvestris
Mouse
Mus musculus
O54781
681
76738
S609
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508534
693
78060
S621
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001165329
695
78154
L623
I
P
R
K
C
A
M
L
G
K
Y
S
K
D
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
K834
I
P
P
S
I
Y
K
K
G
K
H
W
R
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
N636
L
P
S
Y
L
L
R
N
G
K
Y
T
R
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
95.6
N.A.
93.9
N.A.
N.A.
87.8
N.A.
80.7
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
99.4
99.2
96.5
N.A.
95.4
N.A.
N.A.
91.9
N.A.
87.4
N.A.
N.A.
N.A.
N.A.
36
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
60
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
78
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
78
0
% E
% Phe:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
67
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
89
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
12
12
0
100
0
0
12
0
0
% K
% Leu:
12
0
0
0
12
12
67
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
100
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
78
0
0
0
12
0
0
0
0
0
89
0
0
% R
% Ser:
0
0
12
12
0
0
0
67
0
0
0
78
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
12
0
12
0
0
0
0
89
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _